Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10411485 | 0.83 | MEN1 (0.43) | SLC6A3MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL17439463 | 0.78 | KMT2A (0.43) | SLC6A3MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL22190045 | 0.73 | SMN1; SMN2 (0.62) | MEN1KMT2ASMN1; SMN2HIF1ACYP2C19 | |
| Methane SCHEMBL29238356 | 0.72 | SMN1; SMN2 (0.60) | MEN1KMT2ASMN1; SMN2HIF1ACYP2C19 | |
| SCHEMBL3243595 | 0.72 | VNN1 (0.43) | MEN1KMT2ASMN1; SMN2HIF1AHPGD | |
| SCHEMBL29203939 | 0.70 | CYP1A2 (0.37) | MEN1KMT2ASMN1; SMN2HIF1AKDM4E | |
| SCHEMBL29470115 | 0.69 | FDPS (0.41) | SLC6A3MEN1KMT2ASMN1; SMN2HIF1A | |
| SCHEMBL1081535 | 0.69 | CYP1A2 (0.47) | MEN1KMT2ASMN1; SMN2HIF1ACYP2C19 | |
| SCHEMBL1712451 | 0.69 | CYP1A2 (0.47) | MEN1KMT2ASMN1; SMN2HIF1ACYP2C19 | |
| SCHEMBL1712531 | 0.69 | CYP1A2 (0.47) | MEN1KMT2ASMN1; SMN2HIF1ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110769824-B | IL-8 inhibitors for the treatment and/or prophylaxis of bacterial secondary infections | 东佩制药股份公司 | 2023-05-23 | — | — | CN | disclosed |