Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA3 | P07451 | 3/20 | 0.40 |
| ▸ | CA4 | P22748 | 3/20 | 0.40 |
| ▸ | CA6 | P23280 | 3/20 | 0.40 |
| ▸ | CA5A | P35218 | 3/20 | 0.40 |
| ▸ | CA7 | P43166 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23050342 | 0.85 | CA12 (0.54) | CA12CA1CA2CA3CA4 | |
| SCHEMBL10292428 | 0.84 | PAOX (0.39) | CA12CA1CA2CA3CA4 | |
| SCHEMBL5307045 | 0.82 | DNM1 (0.48) | CA12CA1CA2CA3CA4 | |
| SCHEMBL5306410 | 0.82 | DNM1 (0.48) | CA12CA1CA2CA3CA4 | |
| SCHEMBL10879467 | 0.81 | ALDH1A1 (0.42) | TSHRDNM1GNAI3GNAO1GNAI1 | |
| SCHEMBL8389662 | 0.81 | CA12 (0.40) | CA12CA1CA2CA3CA4 | |
| SCHEMBL6403719 | 0.79 | — | — | |
| SCHEMBL976852 | 0.79 | DNM1 (0.44) | CA12CA1CA2CA3CA4 | |
| SCHEMBL22806820 | 0.79 | GNAI3 (0.47) | PAOXTSHRDNM1GNAI3GNAO1 | |
| SCHEMBL13374807 | 0.79 | GNAI3 (0.47) | PAOXTSHRDNM1GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2809660-B1 | MACROCYCLIC COMPOUNDS FOR MODULATING IL-17 | ENSEMBLE THERAPEUTICS CORP (US) | 2016-01-20 | — | — | EP | disclosed |