Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | HNF4A | P41235 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14338517 | 0.98 | ATM (0.65) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL4301156 | 0.88 | L3MBTL1 (0.53) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL6368724 | 0.88 | VCP (0.57) | ATMTDP1L3MBTL1ALDH1A1PBRM1 | |
| SCHEMBL1927619 | 0.88 | SLC7A11 (0.55) | PTPN11HNF4AAPPCA12CA1 | |
| SCHEMBL6673707 | 0.88 | CES2 (0.52) | ATMTDP1L3MBTL1ALDH1A1PTPN11 | |
| SCHEMBL7716935 | 0.85 | VNN1 (0.47) | ATMTDP1L3MBTL1HNF4ACA12 | |
| SCHEMBL28979629 | 0.84 | PTPN11 (0.49) | ATMTDP1L3MBTL1ALDH1A1PTPN11 | |
| SCHEMBL12182347 | 0.84 | ACACB (0.57) | ALDH1A1PTPN11HNF4AAPPCA12 | |
| SCHEMBL7576350 | 0.83 | MEN1 (0.46) | ATMTDP1L3MBTL1ALDH1A1PTPN11 | |
| SCHEMBL3448794 | 0.83 | CA12 (0.45) | ATMTDP1L3MBTL1PBRM1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10166530-B2 | Use of certain transition metal hyperaccumulator plants for reducing organic compounds in a green manner | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2019-01-01 | — | — | US | disclosed |
| US-20170157594-A1 | USE OF CERTAIN TRANSITION METAL HYPERACCUMULATOR PLANTS FOR REDUCING ORGANIC COMPOUNDS IN A GREEN MANNER | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2017-06-08 | — | — | US | disclosed |
| US-20170157594-A1 | USE OF CERTAIN TRANSITION METAL HYPERACCUMULATOR PLANTS FOR REDUCING ORGANIC COMPOUNDS IN A GREEN MANNER | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2017-06-08 | — | — | US | disclosed |
| WO-2016009116-A1 | USE OF CERTAIN TRANSITION METAL HYPERACCUMULATOR PLANTS FOR REDUCING ORGANIC COMPOUNDS IN A GREEN MANNER | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2016-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10166530-B2 | Use of certain transition metal hyperaccumulator plants for reducing organic compounds in a green manner | SLC39A3, OAT, GLB1 | ATM 3322/4885TDP1 2333/4885L3MBTL1 882/4885 |
| US-20170157594-A1 | USE OF CERTAIN TRANSITION METAL HYPERACCUMULATOR PLANTS FOR REDUCING ORGANIC COMPOUNDS IN A GREEN MANNER | SLC39A3, OAT, GLB1 | ATM 3322/4885TDP1 2333/4885L3MBTL1 882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.