Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23660970 | 0.86 | CA12 (0.41) | CA12CA1CA9CA2SMN1; SMN2 | |
| SCHEMBL19016199 | 0.78 | — | — | |
| SCHEMBL23661363 | 0.78 | MLYCD (0.36) | CA12CA1CA9CA2SMN1; SMN2 | |
| SCHEMBL17453108 | 0.78 | MLYCD (0.35) | CA12CA1CA9CA2SMN1; SMN2 | |
| SCHEMBL17453100 | 0.76 | ALDH1A1 (0.35) | CA12CA1CA9CA2PHGDH | |
| SCHEMBL18942813 | 0.76 | ALDH1A1 (0.35) | CA12CA1CA9CA2PHGDH | |
| SCHEMBL19920498 | 0.73 | CA12 (0.38) | CA12CA1CA9CA2SMN1; SMN2 | |
| SCHEMBL18942815 | 0.73 | CYP1A2 (0.39) | PHGDHALDH1A1MGLLLMNA | |
| SCHEMBL19114901 | 0.73 | CA12 (0.38) | CA12CA1CA9CA2SMN1; SMN2 | |
| SCHEMBL17453112 | 0.73 | CA12 (0.38) | CA12CA1CA9CA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3303435-B1 | HYDROFLUOROOLEFINS AND METHODS OF USING SAME | 3M INNOVATIVE PROPERTIES CO (US) | 2020-11-25 | — | — | EP | disclosed |
| EP-3169745-B1 | HYDROFLUOROETHER OLEFINS AND METHODS OF USING SAME | 3M INNOVATIVE PROPERTIES CO (US) | 2020-04-29 | — | — | EP | disclosed |
| US-10577335-B2 | Allylic terminally unsaturated hydrofluoroamine and allylic terminally unsaturated hydrofluoroether compounds and methods of using the same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2020-03-03 | — | — | US | disclosed |
| US-10385249-B2 | Hydrofluoroether olefins and methods of using same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-08-20 | — | — | US | disclosed |
| US-10344006-B2 | Amine-containing acyclic hydrofluoroethers and methods of using the same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-07-09 | — | — | US | disclosed |
| US-20190040024-A1 | AMINE-CONTAINING ACYCLIC HYDROFLUOROETHERS AND METHODS OF USING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-02-07 | — | — | US | disclosed |
| US-10030185-B2 | Hydrofluoroether olefins and methods of using same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-07-24 | — | — | US | disclosed |
| US-10030185-B2 | Hydrofluoroether olefins and methods of using same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-07-24 | — | — | US | disclosed |
| US-20180141893-A1 | HYDROFLUOROOLEFINS AND METHODS OF USING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-05-24 | — | — | US | disclosed |
| WO-2017155735-A1 | AMINE-CONTAINING CYCLIC HYDROFLUOROETHERS AND METHODS OF USING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-09-14 | — | — | WO | disclosed |
| WO-2017155686-A1 | AMINE-CONTAINING ACYCLIC HYDROFLUOROETHERS AND METHODS OF USING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-09-14 | — | — | WO | disclosed |
| US-20170198186-A1 | HYDROFLUOROETHER OLEFINS AND METHODS OF USING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-07-13 | — | — | US | disclosed |
| US-20170198186-A1 | HYDROFLUOROETHER OLEFINS AND METHODS OF USING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-07-13 | — | — | US | disclosed |
| WO-2017095732-A1 | ALLYLIC TERMINALLY UNSATURATED HYDROFLUOROAMINE AND ALLYLIC TERMINALLY UNSATURATED HYDROFLUOROETHER COMPOUNDS AND METHODS OF USING THE SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-06-08 | — | — | WO | disclosed |
| WO-2016196240-A1 | HYDROFLUOROOLEFINS AND METHODS OF USING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-12-08 | — | — | WO | disclosed |
| WO-2016011220-A1 | HYDROFLUOROETHER OLEFINS AND METHODS OF USING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10030185-B2 | Hydrofluoroether olefins and methods of using same | SLC46A1, FANCF, CYP4F2 | CA12 297/4885CA1 345/4885CA9 1693/4885 |
| US-20180141893-A1 | HYDROFLUOROOLEFINS AND METHODS OF USING SAME | RFC3, RFC2, RFC1 | CA12 1746/4885CA1 2229/4885CA9 3510/4885 |
| US-10577335-B2 | Allylic terminally unsaturated hydrofluoroamine and allylic terminally unsaturated hydrofluoroether compounds and methods of using the same | FPR3, NPFFR1, FFAR3 | CA12 1792/4885CA1 1481/4885CA9 1854/4885 |
| US-10344006-B2 | Amine-containing acyclic hydrofluoroethers and methods of using the same | AFF1, AFF2, FANCF | CA12 718/4885CA1 193/4885CA9 1277/4885 |
| US-10385249-B2 | Hydrofluoroether olefins and methods of using same | SLC46A1, CYP4F2, FANCF | CA12 261/4885CA1 507/4885CA9 1726/4885 |
| US-20190040024-A1 | AMINE-CONTAINING ACYCLIC HYDROFLUOROETHERS AND METHODS OF USING THE SAME | AFF1, AFF2, FANCF | CA12 718/4885CA1 193/4885CA9 1277/4885 |
| US-20170198186-A1 | HYDROFLUOROETHER OLEFINS AND METHODS OF USING SAME | SLC46A1, FANCF, CYP4F2 | CA12 297/4885CA1 345/4885CA9 1693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.