SCHEMBL17454530

SCHEMBL17454530

c1ccc2[nH]c(Cc3cccc4ccccc34)cc2c1

nearest known ligand 0.67

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
AHR P35869 3/20 0.67
PCSK9 Q8NBP7 6/20 0.59
LOXL2 Q9Y4K0 1/20 0.53
ADRA2A P08913 2/20 0.51
ADRA2B P18089 2/20 0.51
ADRA2C P18825 2/20 0.51
ADRA1D P25100 2/20 0.51
ADRA1A P35348 2/20 0.51
ADRA1B P35368 2/20 0.51
CASR P41180 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11039079 0.84 AHR (0.60) AHRPCSK9LOXL2CASR
SCHEMBL29403791 0.81 LOXL2 (0.69) AHRPCSK9LOXL2
SCHEMBL401081 0.81 LOXL2 (0.69) AHRPCSK9LOXL2
SCHEMBL28338445 0.81 LOXL2 (0.69) AHRPCSK9LOXL2
SCHEMBL12852216 0.80 AHR (1.00) AHRPCSK9LOXL2
SCHEMBL29886525 0.80 AHR (1.00) AHRPCSK9LOXL2
SCHEMBL31672301 0.79 AHR (0.62) AHRPCSK9LOXL2
SCHEMBL7499115 0.79 PCSK9 (0.63) AHRPCSK9LOXL2
SCHEMBL7490425 0.79 PCSK9 (0.63) AHRPCSK9LOXL2
SCHEMBL7491887 0.79 PCSK9 (0.63) AHRPCSK9LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022217147-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES ROSENFELD MARK J (US) 2022-10-13 WO claimed
WO-2021179088-A1 TERPENE-ENHANCED COMPOSITIONS AND USES THEREOF HEXO OPERATIONS INC. (CA) 2021-09-16 WO claimed
WO-2021179087-A1 TERPENE-ENHANCED COMPOSITIONS AND USES THEREOF HEXO OPERATIONS INC. (CA) 2021-09-16 WO claimed
WO-2018145219-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING ADDICTIONS BY MEANS OF AVERSIVE COUNTERCONDITIONING SERANI MOSTAZAL JORGE (CL) 2018-08-16 WO claimed
US-20180021247-A1 TOPICAL COMPOSITIONS COMPRISING HYDROXY ACIDS AND CANNABINOIDS FOR SKIN CARE Kannalnnovations LLC (US) 2018-01-25 US claimed
WO-2017027553-A1 TOPICAL COMPOSITIONS COMPRISING HYDROXY ACIDS AND CANNABINOIDS FOR SKIN CARE KannaInnovations LLC (US) 2017-02-16 WO claimed
US-20170042791-A1 TOPICAL COMPOSITIONS COMPRISING HYDROXY ACIDS AND CANNABINOIDS FOR SKIN CARE KannaInnovations LLC (US) 2017-02-16 US claimed
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES Ananda Scientific, Inc. (US) 2025-06-19 US disclosed
WO-2024113046-A1 VAPORIZABLE CANNABINOID COMPOSITIONS ZEST CANNABIS INC. (CA) 2024-06-06 WO disclosed
WO-2024108201-A2 CANNABIGEROLIC ACID (CBGA) AND CANNABIGEROL (CBG) DERIVED PRODUCTS AND METHODS OF USE Bazelet Health Systems, Inc. (US) 2024-05-23 WO disclosed
US-20240139268-A1 HYBRID HASHISH-BASED CONSUMER PRODUCTS HEXO OPERATIONS INC. (CA) 2024-05-02 US disclosed
WO-2024073762-A2 COMPOSITIONS FOR IMPROVING HEALTH SHAMAN NATURALS, LLC (US) 2024-04-04 WO disclosed
US-20240082270-A1 CANNABIGEROL (CBG) PRODUCTS AND METHODS OF USE BAZELET HEALTH SYSTEMS INC (US) 2024-03-14 US disclosed
WO-2020037410-A1 CANNABIS-INFUSED PRODUCT WITH ENHANCED CANNABINOID PROFILE USER EXPERIENCE HEXO OPERATIONS INC. (CA) 2020-02-27 WO disclosed
WO-2020037406-A1 CANNABINOID-CONTAINING CONSUMER PRODUCT SYSTEMS, APPARATUS AND METHODS HEXO OPERATIONS INC. (CA) 2020-02-27 WO disclosed
WO-2020037411-A1 CANNABINOID BASED EMULSION SYSTEMS FOR INFUSED AQUEOUS COMPOSITIONS HEXO OPERATIONS INC. (CA) 2020-02-27 WO disclosed
US-20180021247-A1 TOPICAL COMPOSITIONS COMPRISING HYDROXY ACIDS AND CANNABINOIDS FOR SKIN CARE Kannalnnovations LLC (US) 2018-01-25 US disclosed
WO-2017027553-A1 TOPICAL COMPOSITIONS COMPRISING HYDROXY ACIDS AND CANNABINOIDS FOR SKIN CARE KannaInnovations LLC (US) 2017-02-16 WO disclosed
US-20170042791-A1 TOPICAL COMPOSITIONS COMPRISING HYDROXY ACIDS AND CANNABINOIDS FOR SKIN CARE KannaInnovations LLC (US) 2017-02-16 US disclosed
US-20160025753-A1 ASSAY FOR CANNABINOIDS AND METHODS OF USE THEREOF MICROGENICS CORPORATION 2016-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES CNR2, CNR1, FAAH AHR 359/4885PCSK9 3503/4885LOXL2 1697/4885
US-20170042791-A1 TOPICAL COMPOSITIONS COMPRISING HYDROXY ACIDS AND CANNABINOIDS FOR SKIN CARE CNR2, CNR1, HCAR3 AHR 47/4885PCSK9 1587/4885LOXL2 587/4885
US-20180021247-A1 TOPICAL COMPOSITIONS COMPRISING HYDROXY ACIDS AND CANNABINOIDS FOR SKIN CARE CNR2, CNR1, HCAR3 AHR 47/4885PCSK9 1587/4885LOXL2 587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.