Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TTR | P02766 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.35 |
| ▸ | CBR1 | P16152 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL418343 | 0.83 | FFAR1 (0.40) | SLC6A2HTR1ASLC6A4LMNAMAPT | |
| SCHEMBL869032 | 0.72 | EDNRB (0.37) | SLC6A3 | |
| SCHEMBL10195057 | 0.72 | MRGPRX4 (0.37) | SLC6A2HTR1ASLC6A4LMNAMAPT | |
| SCHEMBL3026367 | 0.69 | PGR (0.39) | PGRALDH1A1 | |
| SCHEMBL867844 | 0.66 | FASN (0.38) | — | |
| SCHEMBL412386 | 0.63 | ALDH1A1 (0.38) | SLC6A4LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL14983793 | 0.63 | SIGMAR1 (0.38) | MAPTPGRMEN1KMT2A | |
| SCHEMBL7186092 | 0.63 | TTR (0.75) | SLC6A2SLC6A4CYP2C9LMNAMAPT | |
| SCHEMBL14587466 | 0.62 | GAA (0.43) | LMNAMAPTHPGDKMT2AALDH1A1 | |
| SCHEMBL14983792 | 0.62 | DGAT1 (0.36) | HPGDPGRL3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2387569-A1 | NOVEL HERBICIDES | Syngenta Limited (GB) | 2011-11-23 | — | — | EP | disclosed |
| WO-2010081755-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-07-22 | — | — | WO | disclosed |