Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.39 |
| ▸ | GJB2 | P29033 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1746441 | 1.00 | L3MBTL1 (0.44) | L3MBTL1MAPTCETPMAPK1GAA | |
| SCHEMBL14939003 | 1.00 | L3MBTL1 (0.44) | L3MBTL1MAPTCETPMAPK1GAA | |
| SCHEMBL17651845 | 1.00 | L3MBTL1 (0.44) | L3MBTL1MAPTCETPMAPK1GAA | |
| SCHEMBL13157184 | 1.00 | L3MBTL1 (0.44) | L3MBTL1MAPTCETPMAPK1GAA | |
| SCHEMBL5309010 | 1.00 | L3MBTL1 (0.44) | L3MBTL1MAPTCETPMAPK1GAA | |
| SCHEMBL1746034 | 0.94 | CETP (0.46) | L3MBTL1MAPTCETPMAPK1GAA | |
| SCHEMBL13157186 | 0.94 | CETP (0.46) | L3MBTL1MAPTCETPMAPK1GAA | |
| SCHEMBL1745771 | 0.94 | CETP (0.46) | L3MBTL1MAPTCETPMAPK1GAA | |
| SCHEMBL13157187 | 0.94 | CETP (0.46) | L3MBTL1MAPTCETPMAPK1GAA | |
| SCHEMBL1746439 | 0.80 | OGA (0.37) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563337-B1 | CARRIER AND TARGETING SYSTEM COMPRISING A SIOSOMAL COMPOSITION FOR INTRACELLULAR DELIVERY AND TARGETING OF ACTIVE SUBSTANCE | SALAMA ZOSER B (DE) | 2017-07-26 | — | — | EP | disclosed |
| EP-2384743-A1 | Siosomal formulation for intracellular delivery and targeting of therapeutic agents | Salama, Zoser B. (DE) | 2011-11-09 | — | — | EP | disclosed |