Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17459281 | 0.79 | KDM4E (0.33) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL17469033 | 0.79 | TSHR (0.30) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL17459294 | 0.79 | KDM4E (0.33) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL17459364 | 0.78 | SLC6A2 (0.41) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL17459339 | 0.78 | SLC22A12 (0.34) | SLC6A4SLC6A2SLC6A3SLC22A12 | |
| SCHEMBL4303829 | 0.77 | SLC6A4 (0.71) | SLC6A4SLC6A2SLC6A3DRD2 | |
| SCHEMBL17469121 | 0.77 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3DRD2 | |
| SCHEMBL17468345 | 0.76 | MAOB (0.42) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL17469027 | 0.76 | MAOB (0.42) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL17459288 | 0.75 | SLC6A2 (0.34) | SLC6A4SLC6A2SLC6A3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |