Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17459281 | 0.85 | KDM4E (0.33) | KDM4ESLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL17469033 | 0.85 | TSHR (0.30) | SLC6A2SLC6A4SLC6A3TSHRNISCH | |
| SCHEMBL17459339 | 0.82 | SLC22A12 (0.34) | SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL17459364 | 0.80 | SLC6A2 (0.41) | KDM4ESLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL17459293 | 0.79 | SLC6A4 (0.46) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17459287 | 0.79 | LTA4H (0.38) | SLC6A2SLC6A4SLC6A3LTA4H | |
| SCHEMBL17469027 | 0.78 | MAOB (0.42) | KDM4ESLC6A2SLC6A4SLC6A3LTA4H | |
| SCHEMBL17468345 | 0.78 | MAOB (0.42) | KDM4ESLC6A2SLC6A4SLC6A3LTA4H | |
| SCHEMBL17469111 | 0.76 | DRD3 (0.40) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17459288 | 0.75 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3TSHRNISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |