Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17468345 | 0.77 | MAOB (0.42) | SLC6A2SLC6A4SLC6A3KIF11LTA4H | |
| SCHEMBL17469027 | 0.77 | MAOB (0.42) | SLC6A2SLC6A4SLC6A3KIF11LTA4H | |
| SCHEMBL17459293 | 0.75 | SLC6A4 (0.46) | SLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL17459294 | 0.75 | KDM4E (0.33) | SLC6A2SLC6A4SLC6A3TSHRNISCH | |
| SCHEMBL17459281 | 0.75 | KDM4E (0.33) | SLC6A2SLC6A4SLC6A3TSHRNISCH | |
| SCHEMBL17469033 | 0.75 | TSHR (0.30) | SLC6A2SLC6A4SLC6A3TSHRNISCH | |
| SCHEMBL17459364 | 0.74 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3TSHRNISCH | |
| SCHEMBL17459339 | 0.74 | SLC22A12 (0.34) | SLC6A2SLC6A4SLC6A3TSHRDRD3 | |
| SCHEMBL17459359 | 0.73 | CYP19A1 (0.34) | SLC6A2SLC6A4SLC6A3TSHRKIF11 | |
| SCHEMBL17469121 | 0.73 | SLC6A4 (0.42) | SLC6A2SLC6A4SLC6A3LTA4HKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |