Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17459294 | 0.82 | KDM4E (0.33) | SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL17459364 | 0.81 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3ALDH1A1SMN1; SMN2 | |
| SCHEMBL17459287 | 0.80 | LTA4H (0.38) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17469111 | 0.80 | DRD3 (0.40) | HSD17B3SLC6A2SLC6A4SLC6A3DRD3 | |
| SCHEMBL17459293 | 0.78 | SLC6A4 (0.46) | SLC22A12SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17459281 | 0.77 | KDM4E (0.33) | SLC6A2SLC6A4SLC6A3ALDH1A1TSHR | |
| SCHEMBL17469033 | 0.77 | TSHR (0.30) | SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL17468345 | 0.77 | MAOB (0.42) | SLC6A2SLC6A4SLC6A3ALDH1A1DRD3 | |
| SCHEMBL17469027 | 0.77 | MAOB (0.42) | SLC6A2SLC6A4SLC6A3ALDH1A1DRD3 | |
| SCHEMBL17459359 | 0.76 | CYP19A1 (0.34) | SLC22A12SLC6A2SLC6A4SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |