Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17468345 | 0.84 | MAOB (0.42) | SLC6A4SLC6A2SLC6A3CYP2D6DRD3 | |
| SCHEMBL17469027 | 0.84 | MAOB (0.42) | SLC6A4SLC6A2SLC6A3CYP2D6DRD3 | |
| SCHEMBL17469000 | 0.82 | MAOB (0.50) | SLC6A4CYP3A4LTA4H | |
| SCHEMBL17459287 | 0.82 | LTA4H (0.38) | SLC6A4SLC6A2SLC6A3LTA4H | |
| SCHEMBL17459309 | 0.82 | LTA4H (0.40) | SLC6A4SLC6A2SLC6A3KDM4ELTA4H | |
| SCHEMBL17459303 | 0.82 | LTA4H (0.38) | SLC6A4SLC6A2SLC6A3LTA4H | |
| SCHEMBL17459409 | 0.82 | SLC6A2 (0.40) | SLC6A4SLC6A2SLC6A3LTA4H | |
| SCHEMBL17459277 | 0.82 | LTA4H (0.38) | SLC6A4SLC6A2SLC6A3KDM4ELTA4H | |
| SCHEMBL17459422 | 0.82 | LMNA (0.48) | SLC6A4SLC6A2SLC6A3DRD2DRD3 | |
| SCHEMBL17469111 | 0.81 | DRD3 (0.40) | SLC6A4SLC6A2SLC6A3DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |