Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 3/20 | 0.51 |
| ▸ | CTSS | P25774 | 3/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL394093 | 0.82 | ALDH1A1 (0.50) | CTSLCTSSCTSBALDH1A1LMNA | |
| SCHEMBL27641460 | 0.81 | CTSL (0.41) | CTSLCTSSCTSBALDH1A1LMNA | |
| SCHEMBL3647693 | 0.81 | CTSL (0.53) | HTTCTSLCTSSCTSBALDH1A1 | |
| SCHEMBL25857104 | 0.81 | CTSL (0.53) | HTTCTSLCTSSCTSBALDH1A1 | |
| SCHEMBL6367600 | 0.81 | ALDH1A1 (0.50) | HTTALDH1A1MEN1KMT2AGAA | |
| SCHEMBL4861409 | 0.81 | CTSL (0.53) | HTTCTSLCTSSCTSBALDH1A1 | |
| SCHEMBL2972573 | 0.80 | ALDH1A1 (0.51) | ALDH1A1KMT2AGAAUSP2HPGD | |
| SCHEMBL14476418 | 0.80 | LMNA (0.55) | HTTCTSLCTSSCTSBALDH1A1 | |
| SCHEMBL14476350 | 0.80 | LMNA (0.55) | HTTCTSLCTSSCTSBALDH1A1 | |
| SCHEMBL6368353 | 0.80 | LMNA (0.50) | CTSLCTSSCTSBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563758-A1 | NEW COMPOUNDS, SYNTHESIS AND USE THEREOF IN THE TREATMENT OF PAIN | LACER, S.A. (ES) | 2013-03-06 | — | — | EP | disclosed |
| US-20130046012-A1 | NEW COMPOUNDS, SYNTHESIS AND USE THEREOF IN THE TREATMENT OF PAIN | LACER, S.A. (ES) | 2013-02-21 | — | — | US | disclosed |
| WO-2011135007-A1 | NEW COMPOUNDS, SYNTHESIS AND USE THEREOF IN THE TREATMENT OF PAIN | LACER, S.A. (ES) | 2011-11-03 | — | — | WO | disclosed |
| EP-2383255-A1 | New compounds, synthesis and use thereof in the treatment of pain | LACER, S.A. (ES) | 2011-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130046012-A1 | NEW COMPOUNDS, SYNTHESIS AND USE THEREOF IN THE TREATMENT OF PAIN | OPRL1, OPRK1, TRPV1 | HTT 1810/4885CTSL 1676/4885CTSS 917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.