Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1876057 | 0.83 | RAB9A (0.47) | TDP1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL1502364 | 0.81 | KDM4E (0.46) | SRD5A2POLBLDHAALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL1502313 | 0.80 | KDM4E (0.45) | POLBKMT2ALDHAALDH1A1GAA | |
| 4-Nitrobenzoic Acid SCHEMBL11648887 | 0.80 | TDP1 (0.81) | TDP1SRD5A2POLBMAPK1CES2 | |
| 4-Nitrobenzoic Acid SCHEMBL3850860 | 0.76 | TDP1 (0.88) | TDP1SRD5A2POLBMAPK1CES2 | |
| SCHEMBL5269547 | 0.75 | IDO1 (0.56) | TDP1ALDH1A1MAPTCSNK2A1 | |
| Terephthalic Acid SCHEMBL27685585 | 0.74 | TDP1 (0.83) | TDP1SRD5A2POLBMAPK1CES2 | |
| Benzoic Acid SCHEMBL27557362 | 0.74 | TDP1 (0.83) | TDP1SRD5A2POLBMAPK1CES2 | |
| 4-Nitrobenzoic Acid SCHEMBL43476 | 0.74 | TDP1 (1.00) | TDP1SRD5A2POLBMAPK1CES2 | |
| Terephthalic Acid SCHEMBL28023943 | 0.74 | TDP1 (1.00) | TDP1SRD5A2POLBMAPK1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11214578-B2 | Urea/carbamates FAAH MAGL or dual FAAH/MAGL inhibitors and uses thereof | NORTHEASTERN UNIVERSITY (US) | 2022-01-04 | — | — | US | disclosed |
| US-20200148696-A1 | Urea/Carbamates FAAH MAGL Or Dual FAAH/MAGL Inhibitors And Uses Thereof | NORTHEASTERN UNIVERSITY | 2020-05-14 | — | — | US | disclosed |
| US-10570146-B2 | Urea/carbamates FAAH MAGL or dual FAAH/MAGL inhibitors and uses thereof | NORTHEASTERN UNIVERSITY (US) | 2020-02-25 | — | — | US | disclosed |
| US-20170247387-A1 | UREA/CARBAMATES FAAH MAGL OR DUAL FAAH/MAGL INHIBITORS AND USES THEREOF | NORTHEASTERN UNIVERSITY | 2017-08-31 | — | — | US | disclosed |
| WO-2016014975-A2 | UREA/CARBAMATES FAAH MAGL OR DUAL FAAH/MAGL INHIBITORS AND USES THEREOF | NORTHEASTERN UNIVERSITY (US) | 2016-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11214578-B2 | Urea/carbamates FAAH MAGL or dual FAAH/MAGL inhibitors and uses thereof | FAAH, FAAH2, MGLL | TDP1 3823/4885SRD5A2 3698/4885POLB 2165/4885 |
| US-10570146-B2 | Urea/carbamates FAAH MAGL or dual FAAH/MAGL inhibitors and uses thereof | FAAH, FAAH2, MGLL | TDP1 3898/4885SRD5A2 4005/4885POLB 3163/4885 |
| US-20170247387-A1 | UREA/CARBAMATES FAAH MAGL OR DUAL FAAH/MAGL INHIBITORS AND USES THEREOF | FAAH, FAAH2, MGLL | TDP1 3625/4885SRD5A2 4199/4885POLB 2815/4885 |
| US-20200148696-A1 | Urea/Carbamates FAAH MAGL Or Dual FAAH/MAGL Inhibitors And Uses Thereof | FAAH, MGLL, FAAH2 | TDP1 3122/4885SRD5A2 4247/4885POLB 2889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.