Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16227069 | 0.82 | KMT2A (0.61) | KMT2ACYP2A13LMNAACHEMEN1 | |
| SCHEMBL12856255 | 0.82 | KMT2A (0.76) | KMT2ACYP2A13LMNAACHEMEN1 | |
| SCHEMBL14983599 | 0.81 | ALDH1A1 (0.62) | KMT2ACYP2A13LMNAMEN1KDM4E | |
| SCHEMBL18704976 | 0.81 | SIGMAR1 (0.65) | KMT2ACYP2A13MEN1KDM4EALDH1A1 | |
| SCHEMBL18704987 | 0.81 | KDM4E (0.48) | KMT2AACHEMEN1KDM4EALDH1A1 | |
| SCHEMBL24403536 | 0.80 | KMT2A (1.00) | KMT2ACYP2A13LMNAACHEMEN1 | |
| SCHEMBL11891934 | 0.80 | KMT2A (0.73) | KMT2ACYP2A13LMNAACHEMEN1 | |
| SCHEMBL29953538 | 0.80 | MPO (0.47) | KMT2AMEN1KDM4EALDH1A1TDP1 | |
| SCHEMBL329437 | 0.80 | KMT2A (0.72) | KMT2ACYP2A13LMNAACHEMEN1 | |
| SCHEMBL18704979 | 0.79 | MEN1 (0.57) | KMT2AMEN1KDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9243040-B2 | Stable helical ionic polypeptides | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-01-26 | — | — | US | disclosed |