Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.62 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.58 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.58 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.56 |
| ▸ | ACACB | O00763 | 4/20 | 0.56 |
| ▸ | ACACA | Q13085 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8262960 | 0.90 | MEN1 (0.60) | HRH4FGFR1FGFR2FGFR3HRH3 | |
| SCHEMBL20765718 | 0.88 | ALDH1A1 (0.67) | HSP90AA1ESR2TDP1FGFR1KDR | |
| SCHEMBL20683090 | 0.86 | HRH4 (0.57) | HRH4FGFR1FGFR2FGFR3HRH3 | |
| SCHEMBL20683046 | 0.84 | HRH4 (0.58) | HRH4FGFR1FGFR2FGFR3HRH3 | |
| SCHEMBL20313106 | 0.82 | TSHR (0.56) | HRH4FGFR1FGFR2FGFR3HRH3 | |
| SCHEMBL16598920 | 0.81 | MAOB (0.56) | HSP90AA1ESR2TDP1MEN1KMT2A | |
| SCHEMBL18341894 | 0.80 | HSD17B10 (0.55) | HRH4FGFR1FGFR2FGFR3HRH3 | |
| SCHEMBL20774926 | 0.80 | ALDH1A1 (0.50) | HSP90AA1ESR2TDP1FGFR1FGFR2 | |
| SCHEMBL13290560 | 0.79 | KMT2A (0.47) | HRH4HSP90AA1ESR2TDP1FGFR1 | |
| SCHEMBL8302208 | 0.79 | L3MBTL3 (0.57) | FGFR1FGFR2FGFR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970158-B1 | ALKYL-HETEROARYL SUBSTITUTED QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISORDERS | BIOELECTRON TECH CORP (US) | 2019-02-20 | — | — | EP | disclosed |
| US-20160024085-A1 | ALKYL-HETEROARYL SUBSTITUTED QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISORDERS | PTC THERAPEUTICS, INC. | 2016-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024085-A1 | ALKYL-HETEROARYL SUBSTITUTED QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISORDERS | NQO1, COQ8A, NDUFAB1 | HRH4 3981/4885HSP90AA1 417/4885ESR2 1461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.