Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | ANPEP | P15144 | 2/20 | 0.34 |
| ▸ | PSMB2 | P49721 | 6/20 | 0.33 |
| ▸ | PSMB10 | P40306 | 4/20 | 0.33 |
| ▸ | KIFC1 | Q9BW19 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834538 | 0.94 | ALDH1A1 (0.38) | ALDH1A1LMNAMAPTMMEANPEP | |
| SCHEMBL22167453 | 0.91 | PSMB2 (0.35) | ALDH1A1LMNAMAPTMMEPSMB2 | |
| SCHEMBL17834899 | 0.90 | ITGB3 (0.39) | MMEANPEPKIFC1 | |
| SCHEMBL17834891 | 0.90 | MME (0.35) | ALDH1A1LMNAMAPTMMEANPEP | |
| SCHEMBL22167483 | 0.90 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTKIFC1CYP2C9 | |
| SCHEMBL17834781 | 0.90 | ITGB3 (0.35) | ALDH1A1LMNAMAPTMMEANPEP | |
| SCHEMBL17834602 | 0.89 | MME (0.36) | ALDH1A1LMNAMAPTMMEANPEP | |
| SCHEMBL17968983 | 0.89 | MME (0.36) | ALDH1A1LMNAMAPTMMEANPEP | |
| SCHEMBL17834510 | 0.89 | MME (0.36) | ALDH1A1LMNAMAPTMMEANPEP | |
| SCHEMBL17968971 | 0.89 | MME (0.36) | ALDH1A1LMNAMAPTMMEANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172199-B1 | PYRIMIDINE DERIVATIVES AS GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-07-01 | — | — | EP | disclosed |
| US-9839664-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2017-12-12 | — | — | US | disclosed |
| US-20170216392-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2017-08-03 | — | — | US | disclosed |
| US-9474755-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SARL (CH) | 2016-10-25 | — | — | US | disclosed |
| US-20160038487-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2016-02-11 | — | — | US | disclosed |
| WO-2016015014-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS, INC. (US) | 2016-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170216392-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | ALDH1A1 4730/4885LMNA 2896/4885MAPT 3992/4885 |
| US-20160038487-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | ALDH1A1 4730/4885LMNA 2896/4885MAPT 3992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.