Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.34 |
| ▸ | PLG | P00747 | 5/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.34 |
| ▸ | KIFC1 | Q9BW19 | 6/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834502 | 0.90 | ITGB3 (0.37) | L3MBTL1KIFC1MAPK14 | |
| SCHEMBL19485671 | 0.90 | ITGB3 (0.37) | L3MBTL1KIFC1MAPK14 | |
| SCHEMBL17468562 | 0.90 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTKIFC1CYP2C9 | |
| SCHEMBL17834580 | 0.89 | DGAT1 (0.36) | L3MBTL1PRSS1PLGPRSS2PRSS3 | |
| SCHEMBL22167260 | 0.89 | L3MBTL1 (0.32) | L3MBTL1PRSS1PLGPRSS2PRSS3 | |
| SCHEMBL22167453 | 0.88 | PSMB2 (0.35) | ALDH1A1LMNAMAPTPRSS1PLG | |
| SCHEMBL22167229 | 0.85 | PLG (0.33) | L3MBTL1PRSS1PLGPRSS2PRSS3 | |
| SCHEMBL17834855 | 0.84 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTKIFC1CYP2C9 | |
| SCHEMBL17834538 | 0.84 | ALDH1A1 (0.38) | ALDH1A1LMNAMAPTL3MBTL1KIFC1 | |
| SCHEMBL22167265 | 0.84 | KLKB1 (0.31) | L3MBTL1PRSS1PLGPRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172199-B1 | PYRIMIDINE DERIVATIVES AS GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-07-01 | — | — | EP | disclosed |