Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1179476 | 0.83 | HPGD (0.38) | HPGDMAPTKMT2ASMN1; SMN2HTT | |
| SCHEMBL6195273 | 0.81 | ALDH1A1 (0.52) | HPGDKMT2AMEN1PTPRCALDH1A1 | |
| SCHEMBL11399787 | 0.79 | C1R (0.35) | KMT2AMEN1PTPRCALDH1A1LMNA | |
| SCHEMBL6193168 | 0.79 | NPC1 (0.37) | MAPTKMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL8550679 | 0.79 | S100A4 (0.33) | MAPTKMT2AMEN1PTPRCHTT | |
| SCHEMBL6194126 | 0.79 | HSD17B10 (0.44) | NPBWR1MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3535919 | 0.79 | ALDH1A1 (0.53) | HPGDMAPTKMT2AMEN1POLB | |
| SCHEMBL6191701 | 0.78 | PTGS2 (0.40) | NPBWR1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL6187312 | 0.78 | HSD17B10 (0.42) | — | |
| SCHEMBL2221801 | 0.77 | HPGD (0.45) | HPGDMAPTKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385042-A1 | Prokineticin 1 receptor antagonists | Janssen Pharmaceutica N.V. (BE) | 2011-11-09 | — | — | EP | disclosed |
| US-8039028-B2 | Use of an extract of the orchid Vanda coerulea as a skin hydrating agent | LVMH REACHERCHE (FR) | 2011-10-18 | — | — | US | disclosed |
| EP-1585727-A1 | INDOLES USEFUL IN THE TREATMENT OF ANDROGEN-RECEPTOR RELATED DISEASES | Akzo Nobel N.V. (NL) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004041782-A1 | INDOLES USEFUL IN THE TREATMENT OF ANDROGEN-RECEPTOR RELATED DISEASES | AKZO NOBEL N.V. (NL) | 2004-05-21 | — | — | WO | disclosed |
| EP-0008540-B1 | 2-ARYL-1,3-INDANDIONE DERIVATIVES AND COMPOSITIONS COMPRISING THEM FOR CONTROLLING ECTOPARASITIC ACARINA | UNION CARBIDE CORPORATION (US) | 1984-10-24 | — | — | EP | disclosed |
| EP-0011048-B1 | A PROCESS FOR THE MANUFACTURE OF SUBSTANTIALLY PURE 3-AMINO-4-ALKOXY-ACYLANILIDES FROM 2,4-DINITROCHLOROBENZENE | Toms River Chemical Corporation (US) | 1982-01-27 | — | — | EP | disclosed |