Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1R | P00736 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 3/20 | 0.31 |
| ▸ | S100A4 | P26447 | 3/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2193445 | 0.83 | LMNA (0.33) | ALDH1A1TDP1LMNAMEN1KMT2A | |
| SCHEMBL6195273 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TDP1TP53CYP1A2CYP3A4 | |
| SCHEMBL6194126 | 0.79 | HSD17B10 (0.44) | ALDH1A1TDP1LMNACYP3A4MAPK1 | |
| SCHEMBL6193168 | 0.79 | NPC1 (0.37) | ALDH1A1TDP1LMNATP53CYP1A2 | |
| SCHEMBL1746864 | 0.79 | NPBWR1 (0.37) | ALDH1A1TDP1LMNAMAPK1PTPRC | |
| SCHEMBL3535919 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TDP1LMNATP53CYP1A2 | |
| SCHEMBL9516590 | 0.77 | ALDH1A1 (0.47) | ALDH1A1TDP1CYP3A4MEN1KMT2A | |
| SCHEMBL6192438 | 0.76 | ESR2 (0.37) | ALDH1A1TDP1CYP1A2MEN1KMT2A | |
| SCHEMBL7747225 | 0.73 | GPR35 (0.46) | ALDH1A1TDP1HSD17B10PTPRCS100A4 | |
| SCHEMBL6683239 | 0.72 | HTR7 (0.42) | ALDH1A1TDP1LMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0016799-A1 | DETERMINATION OF TRIGLYCERIDES AND ENZYME REAGENTS | MERCK PATENT GmbH (DE) | 1980-10-15 | — | — | EP | claimed |
| EP-0016799-A4 | DETERMINATION OF TRIGLYCERIDES AND ENZYME REAGENTS. | MERCK PATENT GMBH (DE) | 1980-10-09 | — | — | EP | claimed |
| WO-1980000260-A1 | DETERMINATION OF TRIGLYCERIDES AND ENZYME REAGENTS | AMERICAN HOSPITAL SUPPLY CORP (US) | 1980-02-21 | — | — | WO | claimed |