Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232168 | 0.80 | ALDH1A1 (0.36) | S100A4TDP1PTPRCALDH1A1MAPT | |
| SCHEMBL1746864 | 0.79 | NPBWR1 (0.37) | TDP1PTPRCKMT2AALDH1A1MEN1 | |
| SCHEMBL15638311 | 0.78 | S100A4 (0.36) | S100A4TDP1PTPRCKMT2AALDH1A1 | |
| SCHEMBL6191701 | 0.78 | PTGS2 (0.40) | TDP1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL1179476 | 0.76 | HPGD (0.38) | TDP1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL3535919 | 0.75 | ALDH1A1 (0.53) | TDP1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL6187312 | 0.74 | HSD17B10 (0.42) | — | |
| SCHEMBL6192325 | 0.74 | ALDH1A1 (0.45) | TDP1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL6195273 | 0.74 | ALDH1A1 (0.52) | S100A4TDP1PTPRCKMT2AALDH1A1 | |
| SCHEMBL6194126 | 0.72 | HSD17B10 (0.44) | TDP1ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376218-B1 | Racemization free attachment of amino acids to solid phase | PERSEPTIVE BIOSYSTEMS INC (US) | 1999-02-24 | — | — | EP | claimed |