SCHEMBL17468979

SCHEMBL17468979

CCOC(=O)C1(N(N)C(=O)C=C(C)C)COC1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.33
TSHR P16473 1/20 0.31
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17468978 0.87 MEN1 (0.34) MEN1NPC1RAB9AKMT2A
SCHEMBL17468974 0.84
SCHEMBL17469132 0.75 SOAT1 (0.32)
SCHEMBL17469133 0.72 OPRM1 (0.30)
SCHEMBL13467944 0.66 ATM (0.42) ATMTSHRMEN1RAB9AKMT2A
SCHEMBL9206727 0.65
SCHEMBL1538030 0.63 ATM (0.43) ATMTSHRMEN1KMT2A
SCHEMBL15482805 0.63 ATM (0.33) ATM
SCHEMBL9856940 0.63 ALDH1A1 (0.46) ATMTSHRMEN1KMT2A
SCHEMBL3472392 0.62 ATM (0.42) ATMTSHRMEN1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016012362-A1 SUBSTITUTED CYANO CYCLOALKYL PENTA-2,4-DIENES, CYANO CYCLOALKYL PENT-2-EN-4-YNES, CYANO HETEROCYCLYL PENTA-2,4-DIENES AND CYANO HETEROCYCLYL PENT-2-EN-4-YNES AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-01-28 WO disclosed