SCHEMBL17469118

SCHEMBL17469118

CCN1Cc2cccc(OC)c2OC(c2ccc(Cl)cc2)C1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 5/20 0.36
DRD4 P21917 3/20 0.36
ADRA1D P25100 3/20 0.35
ADRA1A P35348 3/20 0.35
ADRA1B P35368 3/20 0.35
DRD2 P14416 2/20 0.34
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17469112 0.82 KDM4E (0.38) HTR1ADRD4ADRA1DADRA1AADRA1B
SCHEMBL17459409 0.78 SLC6A2 (0.40)
SCHEMBL17469070 0.75 GUSB (0.41) ALDH1A1
SCHEMBL17469150 0.75 MGLL (0.35)
SCHEMBL17469119 0.75 HRH3 (0.41)
SCHEMBL17469114 0.75 MAOB (0.41) DRD4DRD2
SCHEMBL17468765 0.74 SLC6A4 (0.38) HTR1AALDH1A1
SCHEMBL17469000 0.71 MAOB (0.50)
SCHEMBL17469110 0.71 DRD3 (0.36) DRD2
SCHEMBL17469113 0.71 KIF11 (0.40) DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016012333-A1 PESTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2016-01-28 WO disclosed