Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 6/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17469114 | 0.91 | MAOB (0.41) | HRH3MAOBCYP19A1CYP3A4SLC6A4 | |
| SCHEMBL17469000 | 0.81 | MAOB (0.50) | HRH3MAOBCYP19A1CYP3A4ABCB1 | |
| SCHEMBL17459409 | 0.81 | SLC6A2 (0.40) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL17469165 | 0.78 | MAOB (0.47) | HRH3MAOBCYP19A1CYP3A4ABCB1 | |
| SCHEMBL17469070 | 0.78 | GUSB (0.41) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL17459422 | 0.76 | LMNA (0.48) | MAOBCYP19A1ABCB1ARABCG2 | |
| SCHEMBL17469158 | 0.75 | GABRA1 (0.39) | HRH3MAOBCYP19A1CYP3A4ABCB1 | |
| SCHEMBL17469112 | 0.75 | KDM4E (0.38) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL17469118 | 0.75 | HTR1A (0.36) | — | |
| SCHEMBL17468806 | 0.74 | MAOB (0.44) | MAOBCYP19A1CYP3A4ABCB1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |