Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 4/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17469110 | 0.86 | DRD3 (0.36) | LTA4HDRD2 | |
| SCHEMBL17469113 | 0.85 | KIF11 (0.40) | LTA4HDRD2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17469123 | 0.84 | KIF11 (0.34) | LTA4HDRD2 | |
| SCHEMBL17469109 | 0.84 | KIF11 (0.34) | ALDH1A1HPGDLTA4HDRD2 | |
| SCHEMBL17469120 | 0.83 | LTA4H (0.34) | LTA4H | |
| SCHEMBL17469108 | 0.82 | KIF11 (0.33) | LTA4HDRD2 | |
| SCHEMBL17468921 | 0.82 | LTA4H (0.37) | LTA4HDRD2 | |
| SCHEMBL17469118 | 0.82 | HTR1A (0.36) | ALDH1A1DRD4DRD2HTR1AADRA1D | |
| SCHEMBL17459409 | 0.78 | SLC6A2 (0.40) | LTA4HSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17469070 | 0.75 | GUSB (0.41) | KDM4EALDH1A1HPGDLTA4HSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |