SCHEMBL17469120

SCHEMBL17469120

CCN1Cc2c(cccc2C(F)(F)F)OC(c2ccc(Cl)cc2)C1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 9/20 0.34
CNR2 P34972 2/20 0.34
KIF11 P52732 1/20 0.33
TP53 P04637 1/20 0.32
FADS1 O60427 1/20 0.32
MGLL Q99685 1/20 0.32
P2RX7 Q99572 1/20 0.31
DRD3 P35462 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17468998 0.90 KIF11 (0.42) LTA4HCNR2KIF11TP53DRD3
SCHEMBL17468999 0.86 TSHR (0.39) LTA4HTP53
SCHEMBL17469110 0.85 DRD3 (0.36) LTA4HKIF11DRD3
SCHEMBL17469113 0.84 KIF11 (0.40) LTA4HKIF11DRD3
SCHEMBL17469112 0.83 KDM4E (0.38) LTA4H
SCHEMBL17469109 0.83 KIF11 (0.34) LTA4HKIF11DRD3
SCHEMBL17469123 0.83 KIF11 (0.34) LTA4HKIF11DRD3
SCHEMBL17469108 0.81 KIF11 (0.33) LTA4HKIF11DRD3
SCHEMBL17468921 0.81 LTA4H (0.37) LTA4HCNR2KIF11DRD3
SCHEMBL17459409 0.77 SLC6A2 (0.40) LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016012333-A1 PESTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2016-01-28 WO disclosed