SCHEMBL17469123

SCHEMBL17469123

CCN1Cc2c(I)cccc2OC(c2ccc(Cl)cc2)C1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.34
LTA4H P09960 14/20 0.34
DRD3 P35462 1/20 0.32
DRD2 P14416 1/20 0.32
GUSB P08236 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17469110 0.88 DRD3 (0.36) KIF11LTA4HDRD3DRD2
SCHEMBL17469113 0.87 KIF11 (0.40) KIF11LTA4HDRD3DRD2
SCHEMBL17469109 0.86 KIF11 (0.34) KIF11LTA4HDRD3DRD2GUSB
SCHEMBL17469108 0.84 KIF11 (0.33) KIF11LTA4HDRD3DRD2
SCHEMBL17468921 0.84 LTA4H (0.37) KIF11LTA4HDRD3DRD2GUSB
SCHEMBL17469112 0.84 KDM4E (0.38) LTA4HDRD2
SCHEMBL17469120 0.83 LTA4H (0.34) KIF11LTA4HDRD3
SCHEMBL17459409 0.80 SLC6A2 (0.40) LTA4HGUSB
SCHEMBL17469070 0.77 GUSB (0.41) LTA4HGUSB
SCHEMBL17459303 0.73 LTA4H (0.38) LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016012333-A1 PESTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2016-01-28 WO disclosed