Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17469274 | 0.87 | CYP3A4 (0.38) | MTNR1AMTNR1BBCHEDYRK1AHDAC6 | |
| SCHEMBL17469282 | 0.87 | NQO2 (0.45) | MTNR1AMTNR1BBCHETUBB4ATUBB | |
| SCHEMBL17469285 | 0.87 | CFTR (0.41) | MTNR1ABCHEDYRK1ADYRK3DYRK2 | |
| SCHEMBL17469281 | 0.86 | BCHE (0.36) | MTNR1ABCHEDYRK1ATUBB4ATUBB | |
| SCHEMBL17469275 | 0.86 | BCHE (0.36) | BCHEDYRK1ADYRK3CDK9DYRK2 | |
| SCHEMBL19317484 | 0.84 | ENPP3 (0.40) | ENPP3ENPP1MAPT | |
| SCHEMBL19322129 | 0.84 | GAA (0.40) | BCHETUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17469286 | 0.82 | BCHE (0.36) | MTNR1AMTNR1BBCHEDYRK1APDE3B | |
| SCHEMBL17469276 | 0.81 | MTNR1A (0.43) | MTNR1AMTNR1BBCHETUBB4ATUBB | |
| SCHEMBL19322108 | 0.77 | ALDH1A1 (0.49) | MTNR1AMTNR1BBCHETUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170253580-A1 | ORGANIC REACTIONS | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2017-09-07 | — | — | US | disclosed |
| WO-2016014426-A1 | ORGANIC REACTIONS | THE ARIZONA BOARD OF REGENTS (US) | 2016-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170253580-A1 | ORGANIC REACTIONS | MYC, CYP2E1, CYP3A4 | ENPP3 1199/4885ENPP1 1282/4885MTNR1A 3861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.