Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.44 |
| ▸ | GRM6 | O15303 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17459518 | 0.83 | DHODH (0.39) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL17459517 | 0.83 | DHODH (0.39) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL17469388 | 0.80 | POLB (0.46) | MAPTALDH1A1HPGDGAAKDM4E | |
| SCHEMBL17469387 | 0.75 | RAB9A (0.45) | MAPTALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL13140800 | 0.74 | CYP3A4 (0.61) | MAPTALDH1A1HPGDGAAKDM4E | |
| SCHEMBL9674874 | 0.73 | GSTO1 (0.45) | MAPTALDH1A1HPGDGAAKDM4E | |
| SCHEMBL17469413 | 0.73 | ALDH1A1 (0.54) | MAPTALDH1A1HPGDGAAKDM4E | |
| SCHEMBL17459520 | 0.71 | BCL2L1 (0.46) | MAPTALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL17459521 | 0.71 | BCL2L1 (0.46) | MAPTALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL3510029 | 0.70 | RAB9A (0.57) | MAPTALDH1A1HPGDGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016013976-A1 | METHOD OF FORMING A MULTI-SUBSTITUTED BENZENE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-01-28 | — | — | WO | disclosed |