Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL349476 | 0.83 | ALDH1A1 (0.50) | ELANESMN1; SMN2KDM4EGAAACHE | |
| SCHEMBL19476168 | 0.81 | HTR1A (0.40) | SMN1; SMN2KDM4EGAAACHE | |
| SCHEMBL19175981 | 0.80 | PPARG (0.44) | ACHEALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL19476025 | 0.75 | PARP10 (0.47) | L3MBTL1KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL19476026 | 0.75 | KDM4E (0.63) | ELANESMN1; SMN2KDM4EGAAMAPT | |
| SCHEMBL19476057 | 0.74 | MAOB (0.48) | PTPN1 | |
| SCHEMBL17469676 | 0.72 | CES2 (0.40) | ELANEAHRCYSLTR2CYSLTR1SMN1; SMN2 | |
| SCHEMBL15356757 | 0.70 | L3MBTL1 (0.66) | ELANEAHRL3MBTL1KDM4EMAPT | |
| SCHEMBL13752638 | 0.70 | ALDH1A1 (0.49) | ELANEAHRL3MBTL1KDM4EGAA | |
| SCHEMBL2334456 | 0.68 | METAP1 (0.57) | SMN1; SMN2L3MBTL1KDM4EGAAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170210699-A1 | PREPARATION AND BIOLOGICAL EVALUATION OF VIRIDICATUMTOXIN ANALOGS | WILLIAM MARSH RICE UNIVERSITY (US) | 2017-07-27 | — | — | US | disclosed |
| WO-2016014643-A1 | PREPARATION AND BIOLOGICAL EVALUATION OF VIRIDICATUMTOXIN ANALOGS | WILLIAM MARSH RICE UNIVERSITY (US) | 2016-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170210699-A1 | PREPARATION AND BIOLOGICAL EVALUATION OF VIRIDICATUMTOXIN ANALOGS | VIP, DDOST, ANTXR2 | ELANE 499/4885AHR 3608/4885CYSLTR2 3725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.