Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28513100 | 0.90 | MAPK1 (0.49) | MAPK1ALDH1A1HPGDPOLBCYP2C19 | |
| SCHEMBL1404979 | 0.88 | ALDH1A1 (0.54) | MAPK1ALDH1A1HPGDPOLBCYP2C19 | |
| SCHEMBL15300096 | 0.84 | SMN1; SMN2 (0.44) | MAPK1ALDH1A1HPGDPOLBCYP2C19 | |
| SCHEMBL7379444 | 0.83 | TSHR (0.51) | MAPK1ALDH1A1HPGDPOLBCYP2C19 | |
| SCHEMBL15697660 | 0.83 | L3MBTL1 (0.65) | ALDH1A1HPGDPOLBCYP2C19SMN1; SMN2 | |
| SCHEMBL5101721 | 0.82 | ALDH1A1 (0.53) | MAPK1ALDH1A1HPGDPOLBCYP2C19 | |
| SCHEMBL11175115 | 0.82 | KEAP1 (0.48) | MAPK1ALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL31226210 | 0.82 | NR1H4 (0.59) | MAPK1ALDH1A1HPGDPOLBCYP2C19 | |
| SCHEMBL3054871 | 0.82 | NR1H4 (0.59) | MAPK1ALDH1A1HPGDPOLBCYP2C19 | |
| SCHEMBL11263494 | 0.82 | KEAP1 (0.48) | MAPK1ALDH1A1HPGDPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9504669-B2 | Spliceostatin analogs and methods for their preparation | PFIZER INC. (US) | 2016-11-29 | — | — | US | disclosed |
| US-20160022626-A1 | SPLICEOSTATIN ANALOGS AND METHODS FOR THEIR PREPARATION | PFIZER (US) | 2016-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160022626-A1 | SPLICEOSTATIN ANALOGS AND METHODS FOR THEIR PREPARATION | SF3B5, SNRPA1, SF3B1 | MAPK1 4153/4885ALDH1A1 3045/4885HPGD 4238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.