Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.79 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.70 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.70 |
| ▸ | PGR | P06401 | 2/20 | 0.68 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.67 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | GNA15 | P30679 | 1/20 | 0.58 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.56 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5488236 | 0.88 | HDAC1 (1.00) | HDAC1PGRTDP1MEN1KMT2A | |
| SCHEMBL1232960 | 0.87 | NR1H4 (0.71) | HDAC1FFAR1FFAR4NR1H4TDP1 | |
| SCHEMBL22192258 | 0.85 | PGR (0.93) | HDAC1PGRNR1H4MEN1KMT2A | |
| SCHEMBL1747191 | 0.85 | HDAC1 (0.69) | HDAC1SRD5A2PGRNR1H4TDP1 | |
| SCHEMBL1747309 | 0.84 | RAB9A (0.78) | FFAR1FFAR4NR1H4TDP1MEN1 | |
| SCHEMBL2774842 | 0.84 | FFAR1 (1.00) | FFAR1SRD5A2FFAR4TDP1GNA15 | |
| SCHEMBL22987223 | 0.84 | HPGD (0.74) | HDAC1FFAR1SRD5A2FFAR4NR1H4 | |
| SCHEMBL3142959 | 0.84 | KDM4E (0.65) | HDAC1FFAR1SRD5A2FFAR4NR1H4 | |
| SCHEMBL155094 | 0.83 | PGR (0.72) | HDAC1PGRNR1H4MEN1KMT2A | |
| SCHEMBL17084712 | 0.83 | PGR (0.72) | HDAC1PGRNR1H4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1559422-B1 | RECEPTOR FUNCTION CONTROLLING AGENT | TAKEDA PHARMACEUTICAL (JP) | 2014-04-30 | — | — | EP | disclosed |
| EP-2385032-A1 | GPR40 Receptor function regulator | Takeda Pharmaceutical Company Limited (JP) | 2011-11-09 | — | — | EP | disclosed |
| US-7960369-B2 | Receptor function regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-06-14 | — | — | US | disclosed |
| US-20090012093-A1 | Receptor Function Regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-01-08 | — | — | US | disclosed |
| EP-1559422-A1 | RECEPTOR FUNCTION CONTROLLING AGENT | Takeda Pharmaceutical Company Limited (JP) | 2005-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012093-A1 | Receptor Function Regulator | GPR119, GIPR, INSR | HDAC1 2106/4885FFAR1 33/4885SRD5A2 1727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.