Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NR1I3 | Q14994 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 6/20 | 0.38 |
| ▸ | MMP3 | P08254 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1114945 | 0.83 | RAB9A (0.56) | RAB9AKMT2ACYP1A2ADRA2AMAOA | |
| SCHEMBL17472010 | 0.80 | CA12 (0.38) | NR1I3ALDH1A1GAACA12CA1 | |
| SCHEMBL17472011 | 0.79 | CA12 (0.37) | NR1I3CA12CA1CA9MAP4K4 | |
| SCHEMBL3005279 | 0.78 | CYP1A2 (0.66) | RAB9AKMT2ACYP1A2ADRA2AMAOA | |
| SCHEMBL13612901 | 0.78 | RAB9A (0.50) | RAB9AKMT2ACYP1A2ADRA2AMAOA | |
| SCHEMBL3978167 | 0.77 | RAB9A (0.52) | RAB9AKMT2ACYP1A2ADRA2AMAOA | |
| SCHEMBL13172023 | 0.76 | RAB9A (0.35) | RAB9AKMT2ACYP1A2ADRA2AMAOA | |
| SCHEMBL3977427 | 0.76 | RAB9A (0.48) | RAB9AKMT2ACYP1A2ADRA2AMAOA | |
| SCHEMBL3978151 | 0.75 | RAB9A (0.67) | RAB9AKMT2ACYP1A2ADRA2AMAOA | |
| SCHEMBL3979949 | 0.74 | RAB9A (0.52) | RAB9AKMT2ACYP1A2ADRA2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9381254-B2 | Methods for preparing polymeric reagents | NEKTAR THERAPEUTICS (US) | 2016-07-05 | — | — | US | disclosed |
| US-20160022830-A1 | METHODS FOR PREPARING POLYMERIC REAGENTS | NEKTAR THERAPEUTICS | 2016-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160022830-A1 | METHODS FOR PREPARING POLYMERIC REAGENTS | PAM, ALKBH3, DNPEP | RAB9A 4002/4885KMT2A 1128/4885CYP1A2 3028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.