Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977956 | 0.85 | ALDH1A1 (0.43) | TMEM97SIGMAR1CA2ALDH1A1NPSR1 | |
| SCHEMBL1081573 | 0.83 | TMEM97 (0.45) | TMEM97SIGMAR1CA2ALDH1A1NPSR1 | |
| SCHEMBL1081575 | 0.83 | TMEM97 (0.45) | TMEM97SIGMAR1CA2ALDH1A1NPSR1 | |
| SCHEMBL2458179 | 0.83 | TMEM97 (0.42) | TMEM97SIGMAR1CA2ALDH1A1NPSR1 | |
| SCHEMBL23146060 | 0.83 | SIGMAR1 (0.42) | TMEM97SIGMAR1CA2ALDH1A1NPSR1 | |
| SCHEMBL23146337 | 0.83 | TMEM97 (0.45) | TMEM97SIGMAR1CA2ALDH1A1NPSR1 | |
| SCHEMBL11105943 | 0.83 | TMEM97 (0.56) | TMEM97SIGMAR1CA2ALDH1A1NPSR1 | |
| SCHEMBL7968239 | 0.80 | CA2 (0.46) | TMEM97SIGMAR1CA2ALDH1A1NPSR1 | |
| SCHEMBL7968245 | 0.80 | CA2 (0.46) | TMEM97SIGMAR1CA2ALDH1A1NPSR1 | |
| SCHEMBL27721306 | 0.80 | CA2 (0.46) | TMEM97SIGMAR1CA2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2380890-A1 | New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors | Almirall, S.A. (ES) | 2011-10-26 | — | — | EP | disclosed |
| EP-2380890-A1 | New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors | Almirall, S.A. (ES) | 2011-10-26 | — | — | EP | disclosed |
| US-20110253549-A1 | WASHING APPARATUS AND METHOD OF DEODORIZING WASHING WATER | KANNO MINORU | 2011-10-20 | — | — | US | disclosed |