Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1081573 | 0.87 | TMEM97 (0.45) | TMEM97SIGMAR1CA2ALDH1A1NPSR1 | |
| SCHEMBL1081575 | 0.87 | TMEM97 (0.45) | TMEM97SIGMAR1CA2ALDH1A1NPSR1 | |
| SCHEMBL8977956 | 0.85 | ALDH1A1 (0.43) | TMEM97SIGMAR1CA2ALDH1A1NPSR1 | |
| Benzyl Alcohol SCHEMBL16651422 | 0.84 | SIGMAR1 (0.52) | TMEM97SIGMAR1CA2ALDH1A1NAMPT | |
| SCHEMBL2458179 | 0.83 | TMEM97 (0.42) | TMEM97SIGMAR1CA2ALDH1A1NPSR1 | |
| SCHEMBL23146060 | 0.83 | SIGMAR1 (0.42) | TMEM97SIGMAR1CA2ALDH1A1NPSR1 | |
| SCHEMBL1747643 | 0.83 | TMEM97 (0.42) | TMEM97SIGMAR1CA2ALDH1A1NPSR1 | |
| SCHEMBL11105943 | 0.83 | TMEM97 (0.56) | TMEM97SIGMAR1CA2ALDH1A1NPSR1 | |
| SCHEMBL10757960 | 0.80 | TMEM97 (0.46) | TMEM97SIGMAR1CA2ALDH1A1NPSR1 | |
| SCHEMBL22705180 | 0.80 | CA2 (0.42) | TMEM97SIGMAR1CA2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220380370-A1 | XANTHINE CB1 INHIBITORS | GFB (ABC), LLC | 2022-12-01 | — | — | US | disclosed |
| EP-4034101-A1 | XANTHINE CB1 INHIBITORS | Goldfinch Bio, Inc. (US) | 2022-08-03 | — | — | EP | disclosed |
| CN-114727983-A | Xanthine CB1 inhibitors | 金翅雀生物公司 | 2022-07-08 | — | — | CN | disclosed |
| WO-2021062089-A1 | XANTHINE CB1 INHIBITORS | GOLDFINCH BIO, INC. (US) | 2021-04-01 | — | — | WO | disclosed |
| WO-2021062089-A1 | XANTHINE CB1 INHIBITORS | GOLDFINCH BIO, INC. (US) | 2021-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220380370-A1 | XANTHINE CB1 INHIBITORS | CNR1, GPR119, CNR2 | TMEM97 1491/4885SIGMAR1 792/4885CA2 4711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.