Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1081575 | 0.85 | TMEM97 (0.45) | ALDH1A1NPSR1TMEM97SIGMAR1KDM4E | |
| SCHEMBL1747643 | 0.85 | TMEM97 (0.42) | ALDH1A1NPSR1TMEM97SIGMAR1KDM4E | |
| SCHEMBL1081573 | 0.85 | TMEM97 (0.45) | ALDH1A1NPSR1TMEM97SIGMAR1KDM4E | |
| SCHEMBL23146337 | 0.85 | TMEM97 (0.45) | ALDH1A1NPSR1TMEM97SIGMAR1KDM4E | |
| SCHEMBL2458179 | 0.85 | TMEM97 (0.42) | ALDH1A1NPSR1TMEM97SIGMAR1KDM4E | |
| SCHEMBL23146060 | 0.85 | SIGMAR1 (0.42) | ALDH1A1NPSR1TMEM97SIGMAR1KDM4E | |
| SCHEMBL11105943 | 0.84 | TMEM97 (0.56) | ALDH1A1NPSR1TMEM97SIGMAR1KDM4E | |
| SCHEMBL2462990 | 0.81 | TMEM97 (0.43) | ALDH1A1NPSR1TMEM97SIGMAR1KDM4E | |
| SCHEMBL1746183 | 0.80 | TRPA1 (0.44) | ALDH1A1TMEM97SIGMAR1HSD17B10TSHR | |
| SCHEMBL10757960 | 0.79 | TMEM97 (0.46) | ALDH1A1NPSR1TMEM97SIGMAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525480-A | USED FOR DETERMINATION OF HYDROLASES; COLORIMETRIC ANALYSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-06-11 | — | — | US | disclosed |
| US-5334505-A | For colorimetric determination of hydrolases | BOEHRINGER MANNHEIM GMBH (DE) | 1994-08-02 | — | — | US | disclosed |