Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | GRM8 | O00222 | 1/20 | 0.51 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL863168 | 0.89 | MEN1 (0.69) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6575703 | 0.86 | CA1 (0.61) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3959278 | 0.86 | SMN1; SMN2 (0.64) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL14563219 | 0.84 | MEN1 (0.62) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6323372 | 0.84 | ALDH1A1 (0.68) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL17477114 | 0.83 | ALDH1A1 (0.56) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11642601 | 0.81 | MEN1 (0.64) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL10926166 | 0.81 | NPC1 (0.59) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6305740 | 0.81 | SMN1; SMN2 (0.67) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11640630 | 0.80 | MEN1 (0.51) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3180307-B1 | PROCESS FOR THE SYNTHESIS OF DAPSONE AND ITS INTERMEDIATES | SEEGPHARM SA (CH) | 2019-02-13 | — | — | EP | disclosed |
| US-9845289-B2 | Process for the synthesis of Dapsone and its intermediates | SEEGPHARM SA (CH) | 2017-12-19 | — | — | US | disclosed |
| US-20170217883-A1 | PROCESS FOR THE SYNTHESIS OF DAPSONE AND ITS INTERMEDIATES | SEEGPHARM SA (CH) | 2017-08-03 | — | — | US | disclosed |
| EP-3180307-A1 | PROCESS FOR THE SYNTHESIS OF DAPSONE AND ITS INTERMEDIATES | Seegpharm SA (CH) | 2017-06-21 | — | — | EP | disclosed |
| WO-2016016321-A1 | PROCESS FOR THE SYNTHESIS OF DAPSONE AND ITS INTERMEDIATES | SEEGPHARM SA (CH) | 2016-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217883-A1 | PROCESS FOR THE SYNTHESIS OF DAPSONE AND ITS INTERMEDIATES | DHPS, FDPS, DAP3 | KMT2A 4010/4885MEN1 3291/4885SMN1; SMN2 4698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.