Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL75314 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL27901405 | 0.84 | — | — | |
| Formamide SCHEMBL10967419 | 0.83 | KEAP1 (0.39) | KEAP1NOS1KMT2ARAB9ANPC1 | |
| SCHEMBL2551980 | 0.82 | KMT2A (0.40) | KEAP1NOS1KMT2ARAB9ANPC1 | |
| Phosphoric Acid SCHEMBL7647885 | 0.78 | RAB9A (0.42) | KEAP1NOS1KMT2ARAB9ANPC1 | |
| Piperazine SCHEMBL28075211 | 0.74 | KMT2A (0.38) | KEAP1NOS1KMT2ARAB9ANPC1 | |
| Pivalate SCHEMBL28032650 | 0.74 | RAB9A (0.39) | NOS1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27487661 | 0.72 | KMT2A (0.45) | KEAP1NOS1KMT2ARAB9ANPC1 | |
| Pyridine SCHEMBL28098609 | 0.72 | KMT2A (0.45) | KEAP1NOS1KMT2ARAB9ANPC1 | |
| Valine SCHEMBL934212 | 0.71 | SLC7A5 (0.48) | NOS1KMT2ARAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116082307-A | HPK1 inhibitor and application thereof in medicine | 贝达药业股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-113015730-A | Compounds and compositions for treating conditions associated with NLRP activity | 诺华股份有限公司 | 2021-06-22 | — | — | CN | disclosed |
| EP-3186230-A1 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | Dow AgroSciences, LLC (US) | 2017-07-05 | — | — | EP | disclosed |
| EP-3186229-A1 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | Dow AgroSciences LLC (US) | 2017-07-05 | — | — | EP | disclosed |
| EP-3183238-A1 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | Dow AgroSciences LLC (US) | 2017-06-28 | — | — | EP | disclosed |
| EP-3174856-A1 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | Dow AgroSciences LLC (US) | 2017-06-07 | — | — | EP | disclosed |
| CN-105612162-A | Thiazolopyrimidinones as modulators of NMDA receptor activity | HOFFMANN LA ROCHE | 2016-05-25 | — | — | CN | disclosed |
| CN-102844320-B | Heterocyclic compounds | TAKEDA PHARMACEUTICAL CO.,LTD. (JP) | 2016-03-23 | — | — | CN | disclosed |
| WO-2016028328-A1 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | DOW AGROSCIENCES LLC (US) | 2016-02-25 | — | — | WO | disclosed |
| WO-2016018443-A1 | PROCESS FOR THE PREPARATION OF 3-(3-CHLORO-1H-PYRAZOL-1-YL)PYRIDINE | DOW AGROSCIENCES LLC (US) | 2016-02-04 | — | — | WO | disclosed |
| CN-1713819-A | Anthranilamide arthropodicide treatment | DU PONT (US) | 2005-12-28 | — | — | CN | disclosed |
| CN-1678192-A | Arthropodicidal anthranilamides | DU PONT (US) | 2005-10-05 | — | — | CN | disclosed |
| CN-1671703-A | Process for preparing fused oxazinones from ortho-amino aromatic carboxylic acids and carboxylic acids in the presence of sulfonyl chlorides and pyridines | DU PONT (US) | 2005-09-21 | — | — | CN | disclosed |
| CN-1659160-A | Pyrazolecarboxamide insecticides | DU PONT (US) | 2005-08-24 | — | — | CN | disclosed |
| CN-1620450-A | Quinazolinone (di) ones for controlling invertebrate pests | DU PONT (US) | 2005-05-25 | — | — | CN | disclosed |
| CN-1620449-A | Diamide invertebrate pest control agents | DU PONT (US) | 2005-05-25 | — | — | CN | disclosed |
| CN-1549811-A | Ortho-substituted aryl amide compounds for controlling invertebrate pests | ��Ļ���Ű˾ | 2004-11-24 | — | — | CN | disclosed |
| CN-1543455-A | 3-phenoxy-4-pyridazinol derivatives and herbicidal compositions containing the same | 三共农业株式会社 | 2004-11-03 | — | — | CN | disclosed |
| CN-1541063-A | Method for controlling particular insects by applying anthranilamide compounds | ��Ļ���Ű˾ | 2004-10-27 | — | — | CN | disclosed |
| CN-1494530-A | Heterocyclic diamide invertebrate pest control agents | �Ű˾ | 2004-05-05 | — | — | CN | disclosed |