Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL75314 | 0.81 | — | — | |
| Succinic Acid SCHEMBL22123041 | 0.81 | KDM4E (0.45) | RAB9ANPC1JMJD6KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27901405 | 0.79 | — | — | |
| Phosphoric Acid SCHEMBL7647885 | 0.78 | RAB9A (0.42) | RAB9ANPC1JMJD6KMT2ASMN1; SMN2 | |
| SCHEMBL2551980 | 0.77 | KMT2A (0.40) | RAB9ANPC1JMJD6KMT2ASMN1; SMN2 | |
| SCHEMBL12436779 | 0.74 | LMNA (0.40) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL17477604 | 0.74 | KEAP1 (0.39) | RAB9ANPC1JMJD6KMT2ASMN1; SMN2 | |
| Pyridine SCHEMBL28098609 | 0.72 | KMT2A (0.45) | RAB9ANPC1JMJD6KMT2ASMN1; SMN2 | |
| SCHEMBL29296509 | 0.71 | NOS1 (0.50) | RAB9AKMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8244373 | 0.71 | SMN1; SMN2 (0.45) | RAB9ANPC1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104968345-A | 1, 5-naphthyridine derivatives and MELK inhibitors containing 1, 5-naphthyridine derivatives | ONCOTHERAPY SCIENCE INC | 2015-10-07 | — | — | CN | disclosed |