Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | ARG1 | P05089 | 1/20 | 0.30 |
| ▸ | ARG2 | P78540 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL452622 | 0.83 | HCAR2 (0.41) | TSHRALDH1A1GAARAB9APTPN1 | |
| SCHEMBL9065316 | 0.80 | MEN1 (0.32) | TSHRMEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL9065697 | 0.80 | MEN1 (0.32) | TSHRMEN1KMT2ACHRM2CHRM1 | |
| SCHEMBL455718 | 0.80 | ALDH1A1 (0.48) | TSHRALDH1A1L3MBTL1 | |
| SCHEMBL9065849 | 0.80 | CHRM2 (0.34) | TSHRALDH1A1MEN1KMT2ACHRM2 | |
| SCHEMBL456197 | 0.79 | MEN1 (0.48) | TSHRALDH1A1GAAL3MBTL1MEN1 | |
| SCHEMBL11034348 | 0.78 | NAAA (0.47) | TSHRALDH1A1 | |
| SCHEMBL221073 | 0.78 | PTPN1 (0.40) | TSHRALDH1A1GAAPTPN1MEN1 | |
| SCHEMBL9472810 | 0.77 | NAAA (0.50) | TSHRALDH1A1 | |
| SCHEMBL7681803 | 0.77 | NAAA (0.50) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013166-B2 | Preparation and use of aryl alkyl acid derivatives for the treatment of obesity | BAYER HEALTHCARE LLC (US) | 2011-09-06 | — | — | US | disclosed |
| EP-1633722-B1 | PREPARATION AND USE OF ARYL ALKYL ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | BAYER HEALTHCARE LLC (US) | 2011-08-03 | — | — | EP | disclosed |