Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18355409 | 0.96 | DHODH (0.32) | PDE4ADHODH | |
| SCHEMBL18354509 | 0.92 | PDE4A (0.32) | PDE4ADHODH | |
| SCHEMBL18354046 | 0.92 | TSHR (0.35) | DHODH | |
| SCHEMBL16868810 | 0.91 | PDE4A (0.33) | PDE4ADHODH | |
| SCHEMBL18354530 | 0.91 | HTT (0.34) | DHODH | |
| SCHEMBL18354645 | 0.90 | HDAC8 (0.34) | DHODH | |
| SCHEMBL18354409 | 0.90 | DHODH (0.33) | DHODH | |
| SCHEMBL16863522 | 0.90 | MLYCD (0.36) | DHODH | |
| SCHEMBL18354043 | 0.89 | ALDH1A1 (0.35) | DHODH | |
| SCHEMBL18356137 | 0.88 | DHODH (0.31) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975845-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-22 | — | — | US | disclosed |
| US-20180077930-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-22 | — | — | US | disclosed |
| US-9839216-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-12 | — | — | US | disclosed |
| US-20170152214-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-06-01 | — | — | US | disclosed |
| US-9635853-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-05-02 | — | — | US | disclosed |
| US-20170000120-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-01-05 | — | — | US | disclosed |
| US-20160029624-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152214-A1 | INSECTICIDAL COMPOUNDS | ACHE, HDAC6, TUBA3C | PDE4A 1195/4885DHODH 2125/4885 |
| US-20180077930-A1 | INSECTICIDAL COMPOUNDS | ACHE, CYP4X1, ITPR3 | PDE4A 820/4885DHODH 3024/4885 |
| US-20170000120-A1 | INSECTICIDAL COMPOUNDS | ACHE, HDAC6, TUBA3C | PDE4A 1200/4885DHODH 3226/4885 |
| US-20160029624-A1 | INSECTICIDAL COMPOUNDS | ACHE, HDAC6, TUBA3C | PDE4A 1195/4885DHODH 2125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.