SCHEMBL17483464

SCHEMBL17483464

Cc1ccc2nc3n(-c4ccccc4)c4ccccc4n3c2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.47
HTT P42858 1/20 0.47
PDE10A Q9Y233 4/20 0.40
MAPT P10636 2/20 0.40
FGFR1 P11362 1/20 0.40
KMT2A Q03164 3/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
ADORA2B P29275 1/20 0.40
ADORA1 P30542 1/20 0.40
CYP19A1 P11511 1/20 0.39
MEN1 O00255 2/20 0.39
NQO2 P16083 1/20 0.39
ACSS2 Q9NR19 1/20 0.39
ALDH1A1 P00352 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
IKBKB O14920 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18407027 0.94 MAPK1 (0.44) MAPK1HTTPDE10AMAPTFGFR1
SCHEMBL26528427 0.92 ESR1 (0.41) MAPK1HTTMAPTADORA2BADORA1
SCHEMBL26528421 0.92 ESR1 (0.41) MAPK1HTTMAPTADORA2BADORA1
SCHEMBL19521863 0.90 ADORA3 (0.41) MAPK1HTTMAPTKMT2AADORA1
SCHEMBL16441892 0.90 MAPK1 (0.50) MAPK1HTTPDE10AMAPTFGFR1
SCHEMBL26528425 0.88 ADORA1 (0.40) MAPK1HTTMAPTFGFR1KMT2A
SCHEMBL26528426 0.88 KDM4E (0.39) MAPK1HTTMAPTKMT2AADORA2B
SCHEMBL22926687 0.85 ESR1 (0.43) MAPK1HTTMAPTKMT2ARAB9A
SCHEMBL22662015 0.85 ADORA2B (0.44) MAPK1HTTKMT2AADORA2BADORA1
SCHEMBL18407029 0.85 IKBKB (0.40) MAPK1HTTMAPTKMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11793073-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-17 US disclosed
US-11793073-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-17 US disclosed
US-11773320-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-03 US disclosed
US-11773320-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-03 US disclosed
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2023-07-04 US disclosed
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2023-07-04 US disclosed
US-10971687-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-04-06 US disclosed
US-20200274076-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2020-08-27 US disclosed
EP-3174885-B1 2,9-FUNCTIONALIZED BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLES AS HOSTS FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) IDEMITSU KOSAN CO (JP) 2019-10-02 EP disclosed
US-20190189930-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2019-06-20 US disclosed
EP-2993215-B1 Azabenzimidazo[2,1-a]benzimidazoles for electronic applications IDEMITSU KOSAN CO (JP) 2019-06-19 EP disclosed
US-20190161497-A1 SPECIFICALLY SUBSTITUTED BENZOFURO- AND BENZOTHIENOQUINOLINES FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO., LTD. (JP) 2019-05-30 US disclosed
EP-3053918-B1 2-carbazole substituted benzimidazoles for electronic applications IDEMITSU KOSAN CO (JP) 2018-04-11 EP disclosed
EP-3054498-B1 BISIMIDAZODIAZOCINES IDEMITSU KOSAN CO (JP) 2017-09-20 EP disclosed
WO-2016157113-A1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING ARYL- OR HETEROARYLNITRIL GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO., LTD. (JP) 2016-10-06 WO disclosed
WO-2016125110-A1 BISIMIDAZOLODIAZOCINES IDEMITSU KOSAN CO., LTD. (JP) 2016-08-11 WO disclosed
EP-3054498-A1 Bisimidazodiazocines Idemitsu Kosan Co., Ltd. (JP) 2016-08-10 EP disclosed
WO-2016016791-A1 2,9-FUNCTIONALIZED BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLES AS HOSTS FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) IDEMITSU KOSAN CO., LTD (IKC) (JP) 2016-02-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11773320-B2 Organic electroluminescent materials and devices CCNL2, HCN4, HNRNPL MAPK1 1751/4885HTT 1650/4885PDE10A 4503/4885
US-11793073-B2 Host materials for electroluminescent devices MCM6, MCM2, MCM4 MAPK1 2810/4885HTT 4386/4885PDE10A 3476/4885
US-10971687-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, XDH MAPK1 572/4885HTT 4616/4885PDE10A 4746/4885
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes KCNQ2, KCNQ1, KCNQ4 MAPK1 3128/4885HTT 859/4885PDE10A 4030/4885
US-20190189930-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, XDH MAPK1 572/4885HTT 4616/4885PDE10A 4746/4885
US-20200274076-A1 Organic Electroluminescent Materials and Devices CCNL2, HCN4, HNRNPL MAPK1 1907/4885HTT 1606/4885PDE10A 4547/4885
US-20190161497-A1 SPECIFICALLY SUBSTITUTED BENZOFURO- AND BENZOTHIENOQUINOLINES FOR ORGANIC LIGHT EMITTING DIODES KCNQ2, KCNQ1, KCNQ4 MAPK1 3128/4885HTT 859/4885PDE10A 4030/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.