Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 5/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | RET | P07949 | 7/20 | 0.32 |
| ▸ | KDR | P35968 | 5/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14123 | 0.90 | IDH2 (0.37) | P2RY1KCNH2IGF1RS1PR1RET | |
| SCHEMBL17354485 | 0.89 | IGF1R (0.36) | P2RY1IGF1RMAPT | |
| SCHEMBL17354474 | 0.89 | IGF1R (0.40) | P2RY1KCNH2IGF1RRETKDR | |
| SCHEMBL17354151 | 0.88 | S1PR1 (0.39) | P2RY1KCNH2S1PR1KDRFLT3 | |
| SCHEMBL17354473 | 0.87 | IGF1R (0.37) | P2RY1KCNH2IGF1RRETKDR | |
| SCHEMBL13730 | 0.86 | FLT3 (0.34) | IGF1RS1PR1RETKDRFLT3 | |
| SCHEMBL14275 | 0.85 | DGAT2 (0.36) | KCNH2MAPT | |
| SCHEMBL17486581 | 0.84 | IGF1R (0.33) | P2RY1IGF1R | |
| SCHEMBL17486576 | 0.84 | IGF1R (0.35) | P2RY1IGF1R | |
| SCHEMBL17354140 | 0.83 | S1PR1 (0.36) | IGF1RS1PR1RETKDRFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160031828-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | SILICON VALLEY BANK | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160031828-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | MPO, LPO, CAT | P2RY1 3578/4885KCNH2 3637/4885IGF1R 4795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.