Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 10/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18965888 | 0.90 | P2RX3 (0.39) | P2RX3LMNATP53THRBSMN1; SMN2 | |
| SCHEMBL18965877 | 0.87 | TP53 (0.39) | P2RX3LMNATP53THRBSMN1; SMN2 | |
| SCHEMBL17488322 | 0.84 | P2RX3 (0.39) | P2RX3LMNATP53THRBSMN1; SMN2 | |
| SCHEMBL17488256 | 0.84 | CYP3A4 (0.39) | P2RX3LMNATP53 | |
| SCHEMBL17488046 | 0.83 | LMNA (0.40) | P2RX3LMNATP53THRBSMN1; SMN2 | |
| SCHEMBL17488044 | 0.83 | P2RX3 (0.41) | P2RX3LMNATP53THRBSMN1; SMN2 | |
| SCHEMBL17488331 | 0.81 | LMNA (0.39) | P2RX3LMNATP53THRBSMN1; SMN2 | |
| SCHEMBL17488325 | 0.77 | DHODH (0.42) | LMNATP53THRBSMN1; SMN2NPC1 | |
| SCHEMBL17488045 | 0.77 | LMNA (0.38) | P2RX3LMNATP53THRBSMN1; SMN2 | |
| SCHEMBL17488140 | 0.76 | PIK3C3 (0.40) | P2RX3TP53SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |