Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 17/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17488331 | 0.91 | LMNA (0.39) | P2RX3LMNATP53 | |
| SCHEMBL18965985 | 0.86 | CYP3A4 (0.40) | CYP3A4P2RX3LMNATP53 | |
| SCHEMBL17488047 | 0.84 | P2RX3 (0.40) | P2RX3LMNATP53 | |
| SCHEMBL18965888 | 0.84 | P2RX3 (0.39) | P2RX3LMNATP53 | |
| SCHEMBL17488046 | 0.84 | LMNA (0.40) | P2RX3LMNATP53 | |
| SCHEMBL17487851 | 0.83 | NPC1 (0.39) | CYP3A4TP53 | |
| SCHEMBL17488332 | 0.82 | KDR (0.40) | CYP3A4P2RX3LMNATP53 | |
| SCHEMBL17488023 | 0.81 | CYP3A4 (0.47) | CYP3A4P2RX3 | |
| SCHEMBL18965877 | 0.81 | TP53 (0.39) | CYP3A4P2RX3LMNATP53 | |
| SCHEMBL17487846 | 0.80 | LMNA (0.41) | P2RX3LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |