Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | PPARA | Q07869 | 3/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | PPARD | Q03181 | 1/20 | 0.55 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | ACR | P10323 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL18490937 | 0.93 | PTGS1 (0.54) | PTGS1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL20723694 | 0.90 | MGLL (0.65) | PTGS1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL20739904 | 0.90 | MGLL (0.65) | PTGS1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL20739830 | 0.85 | MGLL (0.59) | PTGS1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL20739829 | 0.85 | MGLL (0.59) | PTGS1MEN1KMT2ANPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL17476740 | 0.82 | PTGS1 (0.45) | PTGS1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL17488468 | 0.81 | MGLL (0.51) | MEN1KMT2ANPC1RAB9AMGLL | |
| SCHEMBL17476742 | 0.81 | PTGS1 (0.43) | PTGS1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL12349787 | 0.80 | PTGS1 (0.60) | PTGS1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL22697592 | 0.79 | ALDH1A1 (0.65) | PTGS1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731991-B2 | Augmenting moieties for anti-inflammatory compounds | LEHIGH UNIVERSITY (US) | 2023-08-22 | — | — | US | disclosed |
| US-20200369688-A1 | Augmenting Moieties for Anti-Inflammatory Compounds | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-11-26 | — | — | US | disclosed |
| US-10752582-B2 | Augmenting moieties for anti-inflammatory compounds | LEHIGH UNIVERSITY (US) | 2020-08-25 | — | — | US | disclosed |
| US-20170044096-A1 | Augmenting Moieties for Anti-Inflammatory Compounds | LEHIGH UNIVERSITY | 2017-02-16 | — | — | US | disclosed |
| US-9512068-B2 | Augmenting moieties for anti-inflammatory compounds | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-12-06 | — | — | US | disclosed |
| US-20160031804-A1 | Augmenting Moieties for Anti-Inflammatory Compounds | LEHIGH UNIVERSITY | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11731991-B2 | Augmenting moieties for anti-inflammatory compounds | LTC4S, VCAM1, PTGES | PTGS1 12/4885MEN1 4652/4885KMT2A 3670/4885 |
| US-10752582-B2 | Augmenting moieties for anti-inflammatory compounds | PTGES, PTGES3, LRBA | PTGS1 11/4885MEN1 4522/4885KMT2A 2466/4885 |
| US-20160031804-A1 | Augmenting Moieties for Anti-Inflammatory Compounds | PTGES, ICAM1, VCAM1 | PTGS1 9/4885MEN1 4476/4885KMT2A 2489/4885 |
| US-20170044096-A1 | Augmenting Moieties for Anti-Inflammatory Compounds | PTGES, PTGES3, LRBA | PTGS1 11/4885MEN1 4522/4885KMT2A 2466/4885 |
| US-20200369688-A1 | Augmenting Moieties for Anti-Inflammatory Compounds | LTC4S, VCAM1, PTGES | PTGS1 12/4885MEN1 4652/4885KMT2A 3670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.