Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499456 | 0.86 | HKDC1 (0.35) | ALDH1A1MAPTLMNAHSD17B10CTNNB1 | |
| SCHEMBL16098253 | 0.85 | TBXA2R (0.47) | ALDH1A1MAPTLMNACTNNB1WNT3A | |
| SCHEMBL17499504 | 0.85 | HKDC1 (0.34) | ALDH1A1MAPTLMNAHSD17B10CTNNB1 | |
| SCHEMBL16102246 | 0.83 | RAB9A (0.55) | ALDH1A1MAPTLMNAHSD17B10RAB9A | |
| SCHEMBL16095574 | 0.81 | POLB (0.48) | ALDH1A1MAPTLMNAHSD17B10RAB9A | |
| SCHEMBL15137200 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAHSD17B10RAB9A | |
| SCHEMBL15137199 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAHSD17B10RAB9A | |
| SCHEMBL17499640 | 0.80 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNAHSD17B10RAB9A | |
| SCHEMBL17499695 | 0.80 | MAPT (0.42) | ALDH1A1MAPTLMNAHSD17B10RAB9A | |
| SCHEMBL16095897 | 0.78 | MAPT (0.48) | ALDH1A1MAPTLMNAHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |