Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499149 | 0.86 | ALDH1A1 (0.33) | ALDH1A1MAPTLMNAHSD17B10RAB9A | |
| SCHEMBL17499490 | 0.85 | ALDH1A1 (0.33) | ALDH1A1MAPTLMNAHSD17B10RAB9A | |
| SCHEMBL16102232 | 0.81 | RAB9A (0.44) | ALDH1A1MAPTLMNAHSD17B10NOS3 | |
| SCHEMBL17499520 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAHSD17B10NOS3 | |
| SCHEMBL17499330 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNAHSD17B10NOS3 | |
| SCHEMBL16102246 | 0.78 | RAB9A (0.55) | ALDH1A1MAPTLMNAHSD17B10NOS3 | |
| SCHEMBL17499298 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNAHSD17B10NOS3 | |
| SCHEMBL16099405 | 0.77 | MAPT (0.44) | ALDH1A1MAPTLMNAHSD17B10NOS3 | |
| SCHEMBL16097658 | 0.75 | MAPT (0.42) | ALDH1A1MAPTLMNAHSD17B10NOS3 | |
| SCHEMBL17499695 | 0.75 | MAPT (0.42) | ALDH1A1MAPTLMNAHSD17B10NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |