Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.78 |
| ▸ | LMNA | P02545 | 4/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | RBP4 | P02753 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13894563 | 0.91 | KDM4E (0.78) | KDM4EALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL21595770 | 0.80 | MAPT (0.56) | KDM4EALDH1A1LMNASMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL16095085 | 0.80 | KDM4E (0.56) | KDM4EALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL21595803 | 0.79 | KDM4E (0.56) | KDM4EALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL12401838 | 0.78 | LMNA (0.57) | KDM4EALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL12409192 | 0.78 | LMNA (0.62) | KDM4EALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL21601214 | 0.78 | SLC6A4 (0.53) | KDM4EALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL21601506 | 0.78 | L3MBTL4 (0.56) | KDM4EALDH1A1LMNASMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL2176957 | 0.77 | LMNA (0.60) | KDM4EALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL10253683 | 0.77 | ALDH1A1 (0.82) | KDM4EALDH1A1LMNASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10570148-B2 | N-alkyl-2-phenoxyethanamines, their preparation and use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-02-25 | — | — | US | disclosed |
| US-20180222919-A1 | N-ALKYL-2-PHENOXYETHANAMINES, THEIR PREPARATION AND USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2018-08-09 | — | — | US | disclosed |
| US-9938291-B2 | N-alkyl-2-phenoxyethanamines, their preparation and use | THE TRUSTESS OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2018-04-10 | — | — | US | disclosed |
| US-20160046649-A1 | N-ALKYL-2-PHENOXYETHANAMINES, THEIR PREPARATION AND USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10570148-B2 | N-alkyl-2-phenoxyethanamines, their preparation and use | HRH3, CBR3, KCNH3 | KDM4E 723/4885ALDH1A1 2874/4885LMNA 1859/4885 |
| US-20160046649-A1 | N-ALKYL-2-PHENOXYETHANAMINES, THEIR PREPARATION AND USE | HRH3, CBR3, KCNH3 | KDM4E 723/4885ALDH1A1 2874/4885LMNA 1859/4885 |
| US-20180222919-A1 | N-ALKYL-2-PHENOXYETHANAMINES, THEIR PREPARATION AND USE | HRH3, CBR3, KCNH3 | KDM4E 723/4885ALDH1A1 2874/4885LMNA 1859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.