SCHEMBL17503333

SCHEMBL17503333

CCc1ccc(CC)c2nc(Cl)c(Cl)nc12

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CTRC Q99895 2/20 0.40
TDP1 Q9NUW8 1/20 0.35
ELANE P08246 3/20 0.33
GABRA1 P14867 4/20 0.32
GABRB2 P47870 4/20 0.32
TLR8 Q9NR97 1/20 0.31
PARP1 P09874 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19242233 0.77 ELANE (0.36) CTRCELANEGABRA1GABRB2TLR8
SCHEMBL28174447 0.76 ALDH1A1 (0.34) CTRCTDP1PARP1
SCHEMBL5745630 0.73 CTRC (0.39) CTRCGABRA1GABRB2SMN1; SMN2
SCHEMBL21899425 0.72 P2RX7 (0.31)
SCHEMBL9181886 0.71 CTRC (0.38) CTRCSMN1; SMN2
SCHEMBL18910424 0.70 CTRC (0.36) CTRC
SCHEMBL2036773 0.70 GABRP (0.43) CTRCTDP1GABRA1GABRB2SMN1; SMN2
SCHEMBL28827733 0.69 KMT2A (0.53) GABRA1GABRB2PARP1
SCHEMBL12658946 0.69 CTRC (0.48) CTRCGABRA1GABRB2
SCHEMBL13495961 0.69 SLC40A1 (0.38) CTRCTDP1GABRA1GABRB2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107074896-B Electroluminescent imidazoquinoxaline carbene metal complexes UDC 爱尔兰有限责任公司 2021-04-13 CN disclosed
US-10784448-B2 Electroluminescent imidazo-quinoxaline carbene metal complexes UDC IRELAND LIMITED (IE) 2020-09-22 US disclosed
US-10784448-B2 Electroluminescent imidazo-quinoxaline carbene metal complexes UDC IRELAND LIMITED (IE) 2020-09-22 US disclosed
EP-3466957-A1 OLED COMPRISING AN ELECTROLUMINESCENT IMIDAZO-QUINOXALINE CARBENE METAL COMPLEXES UDC Ireland Limited (IE) 2019-04-10 EP disclosed
EP-3466957-A1 OLED COMPRISING AN ELECTROLUMINESCENT IMIDAZO-QUINOXALINE CARBENE METAL COMPLEXES UDC Ireland Limited (IE) 2019-04-10 EP disclosed
EP-3186264-B1 ELECTROLUMINESCENT IMIDAZO-QUINOXALINE CARBENE METAL COMPLEXES UDC IRELAND LTD (IE) 2018-11-28 EP disclosed
US-20170237020-A1 Electroluminescent Imidazo-Quinoxaline Carbene Metal Complexes BASF SE (DE) 2017-08-17 US disclosed
US-20170237020-A1 Electroluminescent Imidazo-Quinoxaline Carbene Metal Complexes BASF SE (DE) 2017-08-17 US disclosed
US-20170237020-A1 Electroluminescent Imidazo-Quinoxaline Carbene Metal Complexes BASF SE (DE) 2017-08-17 US disclosed
EP-3186264-A1 ELECTROLUMINESCENT IMIDAZO-QUINOXALINE CARBENE METAL COMPLEXES UDC Ireland Limited (IE) 2017-07-05 EP disclosed
WO-2016020516-A1 ELECTROLUMINESCENT IMIDAZO-QUINOXALINE CARBENE METAL COMPLEXES BASF SE (DE) 2016-02-11 WO disclosed
WO-2016020516-A1 ELECTROLUMINESCENT IMIDAZO-QUINOXALINE CARBENE METAL COMPLEXES BASF SE (DE) 2016-02-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10784448-B2 Electroluminescent imidazo-quinoxaline carbene metal complexes OCIAD1, OCIAD2, OXER1 CTRC 2837/4885TDP1 4129/4885ELANE 2639/4885
US-20170237020-A1 Electroluminescent Imidazo-Quinoxaline Carbene Metal Complexes OCIAD1, OCIAD2, OXER1 CTRC 2837/4885TDP1 4129/4885ELANE 2639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.